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Hypothalamic-Pituitary-Somatotropic Axis Research Tesamorelin is a key research tool for probing the hypothalamic-pituitary-somatotropic (HPS) axis — studying how GHRH-R stimulation interacts with somatostatin inhibition to regulate pulsatile GH secretion, and how the complete GHRH sequence influences axis dynamics compared to shorter analogues such as Sermorelin

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