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”‒ Peter Attia This is a framework that we’ve come up with that you could put any peptide into—and there’s 4 buckets Bucket #1: If you’re being intellectually honest, there would be no use case for this peptide You’ve gone through this line of inquiry and you really can’t make a compelling case for it if you’re being honest You can be dishonest and come up with compelling cases for anything These would be things for which you have no viable mechanism of action You just don’t have data, or there’s some theoretical mechanism, or there’s existing data that actually refute it You don’t have any data in humans or you might even have negative data in humans Peter points out reasons for caution, “ Another thing to look for with these peptides is when you get a lot of shifting goalposts for the alleged benefits, these are peptides where they tout one set of benefits and then they, a couple of years later, come out with a new set of benefits and then a new set of benefits and they’re just making up a new story all the time
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In addition, BPC 157 reduced the severity of lipid accumulation in hepatocytes and the extent of coagulative necrosis after CCl 4 administration, which were severe in the controls
