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Materials and Methods Nerve guidance conduits Chitosan/PGLA nerve guidance conduits, which comprise an outer tube of chitosan and luminal fillers of PGLA filaments, were prepared as previously described 28 except that tube-filling filaments were made up of PGLA instead of polyglycolic acid for better biodegradation property
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In endothelial cell models, BPC-157 significantly enhanced ERK1/2 phosphorylation in a dose-dependent manner, leading to increased cellular proliferation, migration, and vascular tube formation — mediated through downstream activation of transcription factors c-Fos, c-Jun, and EGR-1