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Unlike many peptides that degrade rapidly in biological fluids, this sequence demonstrates remarkable resistance to enzymatic breakdown, a property that the arginate salt form enhances even further
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However, treating melanoma cells with the antioxidant, N-acetylcysteine (NAC), diminished the efficacy of 2-AAPA in B16F10 cells [33] and promoted distant metastasis in NSG mice [32]
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