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Probiotics also increase glucagon-like peptide-1 (GLP-1) secretion and decrease insulin resistance to increase glucose metabolism (Leta et al., 2021)
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At 4–5 mo of age, 3xTg-AD mice generally exhibit cognitive impairment but minimal extracellular amyloid-β (Aβ) plaques, whereas the presence of neuropathology in the form of extracellular Aβ plaques is generally noted by 6–8 mo of age
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