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doi: 10.1021/acschembio.2c00317 253 LiKWangMHuangZ-HWangMSunW-YKuriharaHet al
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Evidence shows that the secretion of incretin hormones may be impaired in some patients (particularly secretion of GLP-1 in obese individuals), but the major responsible factor is a loss of beta cell responsiveness to the incretin hormones [4]
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