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Remyelination requires oligodendrocyte progenitor cells (OPCs) to differentiate into mature myelinating OLs, because mature OLs in the adult mammalian CNS are post mitotic and, thus, unable to proliferate in response to injury and to form new myelin sheaths (McTigue and Tripathi, 2008, Keirstead and Blakemore, 1997)

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Thus, good glycemic control is correlated with low mortality in T2DM Covid-19 patients compared to Covid-19 patients with poor glycemic control