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Both the Wnt receptor Frizzled3 and Frizzled6 are expressed in cochlear and vestibular hair cells in the inner ear, and double knockout mice for both receptors display PCP defects more penetrant in the cochlear than vestibular organs (Wang et al., 2006)

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showed that FETPY, a novel diiron(I)sulfur-carbene complex, triggers ferroptosis in OC cells by promoting iron uptake and inducing membrane lipid peroxidation (164)