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Clinical features [2] In infants and children, vitamin B 12 deficiency may present with the following: Neural tube defects Microcephaly Infantile hypotonia, lethargy Irritability, tremors, myoclonus Feeding difficulties, regurgitation, constipation Growth faltering Developmental delay Infants born to pregnant individuals with vitamin B 12 deficiencies may present with symptoms in the first few months of life
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