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Compared to the normal MCF-10A cells, the R001-treated MDA-MB-231 and MDA-MB-468 cells showed significant changes in G6PD at 16–24 h (Fig

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Furthermore, insulin receptor substrate 1 promotes the transcription of tumour stem cell marker SALL4 , implicating it in CCA stemness properties, and its increased levels in human CCA tumours are associated with worse survival 187

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