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The hepatoprotective effects of SAG depend on its ability to reduce the generation of ROS, as well as pro-inflammatory signaling through the de-activation of TLR4/NF-κB signaling (Figure 9)

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In many parts of Africa, South America, and India, communities rely on locally available plants such as Neem ( Azadirachta indica ) for stomach infections, Bael ( Aegle marmelos ) for diarrhea and dysentery, and Castor ( Ricinus communis ) for constipation and colic