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It is now widely accepted that both mutations of oncogenes and tumor suppressor genes lead to the switch into an angiogenic tumor, i.e., the endogenous balance between pro-angiogenic and anti-angiogenic molecules is tipped in favor of angiogenesis (8–10)

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MOTS-c in Relation to Muscle Homeostasis and Physical Activity Mitochondria supply more energy to the muscles during exercise by communicating exercise-induced signals to other organs