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239 A mass spectrometry-based kinetic profiling method performed with a variety of oxidants, including cysteine persulfide (CSSH), 384 reveals a striking asymmetry of trans -persulfidation within each CstR dimer unit within the tetramer, with one side of the dimer reacting and ultimately closing to a cross-linked product far faster than the opposite side of the dimer
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Studies have shown that the co-culture of DC cells with bombesin, a cytokine secreted by tumor cells, significantly decreases the number of DC and causes DC dysfunction by reducing the expression of HLA-DR, CD86, CD83, CD80, and CD40 in DC
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