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Similarly, Wnt4 and Wnt5a promote differentiation of adipocytes (Nishizuka et al., 2008), and Wnt5b together with Wnt5a is shown to inhibit the Wnt/β-catenin signaling and promotes adipogenesis by activating PPARγ (Van Tienen et al., 2009)

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References Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM

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