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Moreover, QBT exerts anti-inflammatory effects by inhibiting the chemokine C-X-C motif ligand 12 (CXCL12)/chemokine C-X-C motif receptor 4 (CXCR4) axis and its downstream Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) and PI3K/Akt/NF-κB pathways, thereby attenuating neuroinflammatory responses both in vivo and in vitro
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