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Sustained-Release H2S Nanospheres Regulate the Inflammatory Microenvironment of Wounds, Promote Angiogenesis and Collagen Deposition, and Accelerate Diabetic Wound Healing | ACS Applied Bio Materials
Protective effect of thymoquinone against cyclophosphamide-induced hemorrhagic cystitis through inhibiting DNA damage and upregulation of Nrf2 expression
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L-NAME: L-Nitro-Arginine Methyl Ester, SBP: Systolic blood pressure, DBP: diastolic blood pressure, MAP: mean arterial pressure, HR: heart rate, BW:body weight, MAPK: mitogen-activated protein kinase, NFκ B: nuclear factor kappa B, PPAR: peroxisome proliferator-activated receptor, α: alpha, γ: gamma, TBARS: thiobarbituric reactive substances, SOD: superoxide dismutase, CAT: catalase, GSH: glutathione peroxidase, BW: body weight, BGL: blood glucose level, FBG: fasting blood glucose, TC: total cholesterol, TG: triglycerides, LDL: low-density lipoprotein, HDL: high-density lipoprotein, ACE: angiotensin-converting enzyme, NADPH: nicotinamide adenine dinucleotide phosphate, ATP: adenine triphosphate Thymoquinone and insulin resistance Insulin resistance (IR), one of the key components of MetS is a metabolic condition wherein peripheral tissues such as the liver, adipose tissue, and skeletal muscles fail to respond adequately to normal insulin levels in the bloodstream, despite sufficient insulin secretion by pancreatic β-cells (99)