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6–9 As a class, DOACs have been shown to be superior or non-inferior to warfarin in terms of efficacy, 10,11 with reduced risk of stroke, intracranial bleeding, and all-cause mortality

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What's new in 2026 is the compounding classification review — driven by the February 27, 2026 RFK Jr announcement and formalized at the July 23-24, 2026 Pharmacy Compounding Advisory Committee meeting