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Key Takeaways Vitamin B12 can usually be taken with or without food, and consistency matters more than the exact hour

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Reported benefits (per available research): Studied in animal (rodent) models for tendon, ligament, and muscle healing, with researchers attributing effects to promotion of angiogenesis and fibroblast activity (preclinical studies from a Croatian research group at the University of Zagreb, spanning several decades) Originally investigated for gastroprotective properties