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Despite a large amount of effort and many publications, most studies have testified effects of the extract pretreatment prior to acute APAP administration on serologic, histologic, and morphologic liver-related outcomes in vivo , but few studies have explored these effects in hepatic cell lines by culturing with the natural products and administrating APAP

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[DOI] [PMC free article] [PubMed] [Google Scholar] Bryja V, Andersson ER, Schambony A, Esner M, Bryjova L, Biris KK, Hall AC, Kraft B, Cajanek L, Yamaguchi TP, et al