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Factors such as individual metabolism, genetics, and overall health can influence how well glutathione works for each individual

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Furthermore, when DNA damage is too severe to repair or DNA repair mechanisms are overwhelmed, various cellular responses are activated, including cell cycle arrest, senescence, apoptosis, autophagy or necrosis [246–248], which are at least partially achieved by regulating the HUS-1-CEP-1-EGL-1-CED-9-CED-4-CED-3 pathway [122] or the PI3K/Akt pathway [138]