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However, another study of twenty-six obese adults with metabolic syndrome randomized to a diet restricted to 2 mg methionine/kg body weight per day and were provided capsules containing placebo or methionine (33 mg/kg body weight per day) resulted in only a 13.8% reduction in plasma methionine concentrations and both groups had similar weight loss and improved metabolic indices (decreased plasma insulin and triglycerides), while the methionine restricted group had significantly higher fat oxidation and reduced hepatic lipid content [183]