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Signaling Pathways in Adipogenesis Several signaling pathways are included in the adipogenesis process, such as the insulin and IGF-1-activated phosphoinositide 3-kinase/protein kinase B (PI3K/AKT), mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) pathways, Wnt/β-catenin signaling, AMP-activated protein kinase (AMPK) pathway, Hedgehog (Hh) signaling, and bone morphogenic protein (BMP) signaling pathways
