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3.6 Endocrine effects The combination of GLP-1 receptor agonists and metformin has not been associated with an increase in the rate or severity of clinically relevant hypoglycemic events [32, 34, 45, 46, 115-122]

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Assignment of the gene (GLCLC) that encodes the heavy subunit of y-glutamylcysteine synthetase to human chromosome 6