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Causes and Risk Factors of MDD and PDD MDD and PDD share most of their underlying risk factors

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Interestingly, an analysis of data collected in the WENBIT study demonstrated that systemic inflammation was associated with an increased degradation of pyridoxal (PL) to 4-pyridoxic acid (PA), supporting the use of the ratio PA:(PL+PLP) as a marker of both vitamin B 6 status and systemic inflammation (57)