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Necrosis, ulceration, stenosis, or perforation can occur and are characterized by malabsorption, pain, and recurrent episodes of bowel obstruction, as well as perforation and infection.[30-32] In general, fractionated radiation doses of 20 Gy to 30 Gy can be delivered to the small bowel without significant long-term morbidity.[33] Doses higher than 40 Gy are associated with a greater risk of bowel obstruction or chronic enterocolitis.[33] Sensitizing chemotherapeutic agents such as dactinomycin or anthracyclines can increase this risk

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10.1002/alz.13859 Alzheimers Dement