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This article collection will highlight the topics discussed during the meeting sessions in a series of mini-review articles: 1) Intracellular pH dynamics and cancer cell behaviors 2) Metformin: A multi-faceted modulator of the epigenetic landscape 3) Metabolic aspects of palladium (II) potential anti-cancer drugs 4) Cysteine and glutathione, challenging cancer cells to death 5) Cysteine metabolism, a hot spot in cancer cell survival 6) Dysregulation of autophagy by inflammatory cytokines and its impact on cancer progression 7) The interplay between immune cell metabolism and function 8) Microbiota manipulation by diet and probiotics as an emerging tool in cancer therapy and management 149,418 Total views 115,750 Article views 31,973 Article downloads 1,695 Topic views About Frontiers Research Topics With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area