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Oxidative stress, dopamine dysregulation and PV neuron impairment in the ventral hippocampus Research using 18 F-dopa Positron Emission Tomography (PET) indicates that clinical high-risk subjects who convert to psychosis show elevated presynaptic dopamine function in the striatum [144] at baseline, and a progressive increase in striatal dopamine function as they transition [145]

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Exogenously expressed FPR1 can be internalized in mouse embryonic fibroblasts (MEFs) lacking β-arrestin1 and 2, but internalized receptors accumulate in endosomes 20