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Exploratory analysis of biochemical secondary endpoints Exploratory data (GSH, sulfur and amino acid compounds) are presented as medians with interquartile range [Q1-Q3]

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The pathophysiology of IC/BPS is poorly understood, and theories include chronic inflammation, autoimmune dysregulation, bacterial cystitis, urothelial dysfunction, deficiency of the glycosaminoglycan (GAG) barrier and urine cytotoxicity