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Coagulation is the physiological process that leads to blood “solidification” through the conversion of soluble fibrinogen into insoluble fibrin through the enzymatic action of the thrombin, derived from conversion from its zymogen prothrombin
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Gene ontology (GO) functional annotation analysis of the 2,699 genes differentially expressed in response to B12 ( Figure S3 ) indicate that, in leukocytes of patients with moderate COVID-19, the vitamin stimulates the antiviral response induced by IFNs, regulates the exacerbated immune response induced by NF-kappaB and favors the inhibition of gene expression
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