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Hydrogen peroxide, ascorbate, and glutathione: building the Foyer–Halliwell–Asada pathway | Planta | Springer Nature Link
Astrocyte proliferation occurs after sustained exposure to damage, whether in the presence of a chronic neurodegenerative process, trauma, ischemic and infectious processes (Sofroniew, 2014)
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93 These small-diameter nociceptors, already sensitized by prostaglandin E2 (PGE2) and bradykinin, relay amplified signals to the dorsal horn of the spinal cord, where they release glutamate and neuropeptides like substance P