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maintenance 10–20 mg daily Gastro-oesophageal reflux disease (symptomatic treatment in the absence of oesophagitis) ▶ ▶ BY MOUTH Adult: 10 mg daily for up to 4 weeks, then 10 mg daily if required Severe oesophagitis ▶ ▶ BY MOUTH Adult: 20 mg once daily for 8 weeks, continue as maintenance treatment if appropriate Severe oesophagitis, refractory to initial treatment ▶ ▶ BY MOUTH Adult: 20 mg twice daily Functional dyspepsia ▶ ▶ BY MOUTH Adult: 10 mg once daily for 4 weeks Uninvestigated dyspepsia ▶ ▶ BY MOUTH Adult: 20 mg once daily for 4 weeks Zollinger–Ellison syndrome ▶ ▶ BY MOUTH Adult: Initially 60 mg once daily, adjusted according to response, doses above 100 mg daily given in 2 divided doses

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