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[DOI] [PubMed] [Google Scholar] Koo JW, Chaudhury D, Han MH, Nestler EJ (2019) Role of Mesolimbic Brain-Derived Neurotrophic Factor in Depression

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Blocking SCD1/FADS2 contributed to increased cellular reactive oxygen species (ROS) and lipid peroxidation through downregulated glutathione peroxidase 4 (GPX4) and the reduced glutathione/oxidized glutathione (GSH/GSSG) ratio in ascites-derived ovarian cancer cells, thereby promoting ferroptosis [62]