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Clinical evidence, supported by advanced imaging techniques such as susceptibility-weighted imaging (SWI) and quantitative susceptibility mapping (QSM), confirms increased iron deposition specifically within the SN of PD patients, particularly in its ventral region, correlating with symptom severity (Martin-Bastida et al., 2017

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The effectiveness of clomipramine hydrochloride for the treatment of OCD was demonstrated in multicenter, placebo-controlled, parallel-group studies, including two 10-week studies in adults and one 8-week study in children and adolescents 10 to 17 years of age

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