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[] In addition to the hepatokines, the hepatocytes-derived EVs are also the essential modulators of the pancreatic islet, for example, the EVs from the liver in HFD-induced obese mice promote the proliferation of β-cell line MIN6 cells, but does not influence their insulin secretion [] [Figure 7]

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Structural basis for strychnine activation of human bitter taste receptor TAS2R46

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