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Glutathione Peroxidase 5 Is Expressed by the Entire Pig Male Genital Tract and Once in the Seminal Plasma Contributes to Sperm Survival and In Vivo Fertility | PLOS One

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At the molecular level, NAC inhibits JNK, a stress kinase activated by ROS and TNF-α, which phosphorylates IRS-1 at serine residues, disrupting PI3K-Akt signaling [82, 83]