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Unsurprisingly, enhancement of the Nrf2 signaling pathway ameliorated AA-induced tubular epithelial cell injury, while down-regulation of the Nrf2 signaling pathway caused the opposite results, fully demonstrating that Nrf2 plays an important role in the AA-induced nephrotoxicity (Huang et al., 2020)
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Carlsen MH, Halvorsen BL, Holte K, Bøhn SK, Dragland S, Sampson L, Willey C, Senoo H, Umezono Y, Sanada C, Barikmo I
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