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Moreover, these scaffolds—particularly calix[n]arenes and cucurbit[n]urils, can be loaded with various bioactive compounds (e.g., small molecules such as curcumin, resveratrol, or TEMPO and antioxidant enzymes such as catalase or glutathione peroxidase), which can either enhance their intrinsic antioxidant activity or facilitate their targeted delivery to specific cells (Lee et al., 2020