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Notably, MY-E@SS also substantially increased key metabolites associated with arachidonic acid metabolism, such as 4,8,12,15-octadecatetraenoic acid (neg_5652) and (9Z)-hexadecenoic acid (neg_6772), along with the antioxidant S-sulfanylglutathione (neg_3986), bringing their concentrations close to normal levels (Fig