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In physiological conditions, the amyloid protein is produced in normal amounts in its soluble form due to cleavage of AβPP by the α -secretase enzyme, and is eliminated by the action of degrading enzymes such as neprilysin, the insulin-degrading enzyme, and the angiotensin converting enzyme I
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Ken feels like a lottery winner in that their two wonderful sons, Greg ’98 , ME ’99, and Eric (Harvard ’00), live within walking distance with the three grandchildren